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Sickle Cell Diseases Clinical Updates 2026 - On Demand 2026
From bedside crises to breakthrough cures, this on-demand update traces how sickled cells drive disease, then builds to action. You’ll describe key mechanisms, recognize acute and lifelong complications, and review current transfusion recommendations with supportive, preventive strategies. We discuss new therapies, including pyruvate kinase activators, stem cell options, and gene-editing advances, and talk frankly about racism and bias to improve outcomes.
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Availability
On-Demand
Expires on Apr 05, 2029
Credit Offered
0.75 CME Credit
0.75 ABIM-MOC Point
0.75 Participation Credit
  • Overview
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  • Accreditation
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Learning Objectives
After completing this activity, learners should be able to:
  1. Describe the pathophysiology of sickle cell disease.
  2. Recognize the acute and chronic complications of sickle cell disease.
  3. Describe the most recent transfusion guidelines for patients with sickle cell disease.
  4. Discuss the novel pharmacological approaches to sickle cell disease, including pyruvate kinase activators, stem cell therapy and newly approved gene-editing therapies.
  5. Talk about the impact of systemic racism and unconscious bias on the health outcomes of patients with sickle cell disease.
Faculty
  • Leila Ndong, MD
Faculty Disclosures
The individuals in control of content for this activity have no relevant relationships with ACCME-defined ineligible companies to disclose unless listed here. Any relevant relationships were mitigated prior to the start of this activity.
CME Credit Statement
The Society of Hospital Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

MOC Credit Statement
Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 0.75  MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

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