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Ventricular Tachycardia and in-Hospital Mortality ...
Ventricular Tachycardia and in-Hospital Mortality Among Intensive Care Unit Patients
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This retrospective cohort study examined whether ventricular tachycardia (VT) detected in ICU patients is associated with 30-day in-hospital mortality, and whether current bedside monitor alerts are accurate enough to identify high-risk patients.<br /><br />The study included 5,679 ICU admissions from an urban academic medical center between September 2013 and April 2015, with 572,574 hours of continuous ECG monitoring. The average patient age was 58 years, 47.6% were female, and 8.9% of admissions ended in 30-day in-hospital death.<br /><br />Researchers compared three VT definitions: <br />1. VT alerts from current bedside ECG monitors, <br />2. VT detected by a new algorithm, and <br />3. “True VT” manually confirmed by expert clinicians.<br /><br />VT was common by bedside monitor alerts (30% of admissions), but less frequent using the new algorithm (15%) and clinician-confirmed true VT (10%). Patients with any VT alert were generally older, less often female, and had more VT-related comorbidities.<br /><br />In unadjusted analyses, all VT types were associated with higher mortality. After adjustment, patients with VT identified by the new algorithm had a 41% higher rate of 30-day in-hospital mortality, and those with true VT had a 32% higher rate. In contrast, VT alerts from the current bedside monitor were not associated with increased mortality.<br /><br />The main conclusion is that the new VT algorithm and clinician-adjudicated true VT better identified patients at increased risk of death than current bedside monitor alerts. The authors suggest this algorithm may improve risk stratification in ICU patients, but it should be prospectively validated, including evaluation of recurrent VT and mortality risk.
Asset Subtitle
Priya A. Prasad
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Author List
Claire Sommargren, David Mortara, Fabio Badilini, Jessica Zègre-Hemsey, Jonas Isakson, Jørgen Kanters, Mary Carey, Michele Pelter, Priya A. Prasad, Salah Al-Zaiti, Yumiko Abe-Jones
Category
Research
Concept
Ventricular Tachycardia
Concept
Mortality
Concept
VT Detection Algorithm
Concept
30-Day In-Hospital Mortality
Concept
ICU Patients
Distinguished
Non-Finalist
Presenter Organization
University of California San Francisco
Presenting Author
Priya A. Prasad
Track
Outcomes Research
Keywords
ventricular tachycardia
ICU patients
30-day in-hospital mortality
continuous ECG monitoring
bedside monitor alerts
new VT algorithm
true VT
risk stratification
retrospective cohort study
clinician-adjudicated VT
Ventricular Tachycardia
Mortality
VT Detection Algorithm
30-Day In-Hospital Mortality
ICU Patients
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