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The Ultrasound Hepato-Jugular Reflux Compared to I ...
The Ultrasound Hepato-Jugular Reflux Compared to Invasive Right Heart Catheterization.
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This prospective observational study across three tertiary academic hospitals evaluated whether ultrasound-measured hepato-jugular reflux (uHJR) and jugular venous pressure (uJVP) can predict invasive hemodynamic measures from right heart catheterization (RHC), especially pulmonary capillary wedge pressure (PCWP). Adult patients scheduled for RHC were enrolled, excluding those with hemodynamic instability, recent cardiac procedures, severe pulmonary hypertension, significant valvular or congenital disease, or advanced kidney/liver disease. Before catheterization, investigators measured uHJR and uJVP by ultrasound; RAP and PCWP from RHC served as reference standards.<br /><br />In 99 analyzed patients, uJVP showed moderate ability to predict elevated right atrial pressure (RAP ≥10 mmHg), with AUC 0.68, while uHJR was slightly lower at AUC 0.64; the difference was not significant. For elevated PCWP (≥15 mmHg), uHJR performed better than uJVP (AUC 0.71 vs 0.67), though this difference was also not statistically significant. However, logistic regression suggested uHJR improved prediction of PCWP more than uJVP did (adjusted OR 2.6 vs 1.2; p=0.001).<br /><br />Clinically useful thresholds were identified: uHJR of 0 cm had a negative likelihood ratio of 0.4 for elevated PCWP, and uHJR of 1.5 cm had a positive likelihood ratio of 4.3. Reproducibility was substantially better for uHJR (kappa 0.76) than for uJVP (kappa 0.11).<br /><br />Overall, ultrasound can measure hepato-jugular reflux, and uHJR appears more reproducible than uJVP. While uJVP remains useful for RAP, uHJR may offer added value for predicting elevated PCWP, especially at key cut points of 0 cm and 1.5 cm. Limitations included a small convenience sample and an indeterminate intermediate range for uHJR.
Asset Subtitle
Rolando Barajas, MPH
Meta Tag
Author List
David S Weisman, Ernest Fischer, Kazi Kalam, Luis M Calderon, Rolando Barajas, MPH, Shiavax J Rao
Category
Research
Concept
Ultrasound Hepato-Jugular Reflux
Concept
Jugular Vein Ultrasound
Concept
Right Atrial Pressure
Concept
Pulmonary Capillary Wedge Pressure
Concept
Intra-abdominal Pressure
Distinguished
Non-Finalist
Presenter Organization
Georgetown University School of Medicine
Presenting Author
Rolando Barajas, MPH
Track
Technology in Hospital Medicine
Keywords
ultrasound hepato-jugular reflux
uHJR
jugular venous pressure
uJVP
right heart catheterization
pulmonary capillary wedge pressure
PCWP
right atrial pressure
hemodynamic prediction
reproducibility
Ultrasound Hepato-Jugular Reflux
Jugular Vein Ultrasound
Right Atrial Pressure
Pulmonary Capillary Wedge Pressure
Intra-abdominal Pressure
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