SHM Converge Scientific Abstract ePoster Gallery-The Silent Risk: Exploring Antidepressant Poisoning-Related Mortality in the U.S. Through CDC Wonder Data: A Deep Dive Into Data (1999-2020)

The Silent Risk: Exploring Antidepressant Poisoning-Related Mortality in the U.S. Through CDC Wonder Data: A Deep Dive Into Data (1999-2020)

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This retrospective study examined U.S. mortality associated with antidepressant poisoning from 1999 to 2020 using CDC WONDER data and ICD-10 T43 codes. The authors focused on adults aged 25 years and older and analyzed age-adjusted mortality rates (AAMRs) by year, sex, race/ethnicity, region, and geography using Joinpoint regression.<br /><br />Overall antidepressant-related mortality increased significantly over time, rising from 1.0 per 100,000 in 1999 to 2.5 in 2020, with an average annual percent change (AAPC) of 4.38%. Death rates were higher in females than males, and the increase over time was steeper among women. By race/ethnicity, non-Hispanic White individuals accounted for the largest number of deaths, but non-Hispanic American Indian populations had the highest overall mortality rate. Regionally, the Northeast and West had the highest AAMRs, while metropolitan and nonmetropolitan areas showed similar rates. Across states, mortality varied widely, from 0.7 in Alabama to 7.4 in West Virginia.<br /><br />The study concludes that antidepressant-related poisoning mortality has risen substantially in the U.S., underscoring the seriousness of the overdose epidemic and the need for broad public health interventions.

Asset Subtitle

Jaymin G. Patel

Meta Tag

Author List Adnan Bhat, Aman Ullah, Atul Kapoor, Ayesha Bhat, Faiza Khalifa, Faizan Ahmed, Hritvik Jain, Husnain Ahmad, Jaymin G. Patel, John N. George, John W. Merriman III, Kainat Aman, Muhammad Arshad, Mushood Ahmed, Naveen Baskaran, Nisar Asmi, Riley G. Jone

Category Research

Concept Antidepressant Poisoning

Concept Mortality Rate

Concept Temporal Trend

Concept Sex

Concept Race

Distinguished Non-Finalist

Presenter Organization University of Florida

Presenting Author Jaymin G. Patel

Track Other

Keywords

antidepressant poisoning

mortality rates

CDC WONDER

ICD-10 T43

age-adjusted mortality

Joinpoint regression

overdose epidemic

sex disparities

racial disparities

regional variation

Antidepressant Poisoning

Mortality Rate

Temporal Trend

Sex

Race