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Take a Conservative Approach to Managing Pneumomed ...
Take a Conservative Approach to Managing Pneumomediastinum in Covid-19 Infection
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Pdf Summary
This case describes a 69-year-old man with COVID-19 pneumonia who developed extensive pneumomediastinum and subcutaneous emphysema during hospitalization. He initially presented for psychiatric concerns and was found to have worsening respiratory status, fever, elevated inflammatory markers, and bilateral lung opacities on chest X-ray. His oxygen requirement progressively increased, leading to ICU transfer and treatment with remdesivir, dexamethasone, therapeutic enoxaparin, and baricitinib. When his D-dimer rose markedly, CT angiography ruled out pulmonary embolism but revealed pneumomediastinum.<br /><br />Cardiothoracic surgery recommended conservative treatment rather than intervention, with close monitoring using daily chest X-rays. The patient gradually improved, the mediastinal air resolved, and he was eventually discharged breathing room air.<br /><br />The report highlights that pneumomediastinum, though rare, is being reported more often in COVID-19 pneumonia. The likely mechanism is the Macklin effect: severe alveolar injury and increased pressure from coughing or labored breathing cause alveolar rupture, allowing air to track along bronchovascular sheaths into the mediastinum. Because the condition is usually self-limited, management is often conservative unless there is persistent air leak or evidence of cardiopulmonary compromise, in which case thoracic surgery may be needed.<br /><br />Overall, the case supports a conservative approach with serial imaging and clinical monitoring for pneumomediastinum in COVID-19 patients.
Asset Subtitle
Komal Khoja
Meta Tag
Author List
Komal Khoja, Pinky Jha, Sarbagya Pandit, Trisha Jethwa
Category
Clinical Vignettes
Concept
Pneumomediastinum
Concept
COVID-19 Pneumonia
Concept
Macklin Effect
Concept
Observation
Concept
Alveolar Rupture
Distinguished
Non-Finalist
Presenter Organization
Medical College of Wisconsin
Presenting Author
Komal Khoja
Track
Adult
Keywords
COVID-19 pneumonia
pneumomediastinum
subcutaneous emphysema
Macklin effect
CT angiography
conservative management
remdesivir
dexamethasone
ICU transfer
thoracic surgery
Pneumomediastinum
COVID-19 Pneumonia
Macklin Effect
Observation
Alveolar Rupture
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