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Take My Breath Away - A Case of Postoperative Hypo ...
Take My Breath Away - A Case of Postoperative Hypoxia
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This case describes a 66-year-old woman who developed unexplained postoperative hypoxia, tachycardia, and hypotension after a cemented right total hip arthroplasty for femoral neck fracture. During cement placement, she had transient hypoxia and hypotension. In the recovery room, bedside ultrasound showed an underfilled, hyperdynamic left ventricle without right heart strain, and lung ultrasound did not show pulmonary edema, effusion, or pneumothorax. She remained hypoxic despite fluids, blood transfusion, and albumin. Chest x-ray and CT pulmonary angiogram were negative for acute cardiopulmonary disease or pulmonary embolism. Mild troponin elevation was attributed to demand ischemia.<br /><br />The final diagnosis was bone cement implantation syndrome (BCIS), a diagnosis of exclusion that commonly occurs during cementation, prosthesis insertion, joint reduction, or tourniquet deflation. BCIS typically presents with hypoxia and hypotension, and in severe cases can cause arrhythmias, loss of consciousness, or cardiac arrest. Reported incidence in cemented arthroplasty is around 25-30%, with higher rates in cemented hip hemiarthroplasty and in patients with cancer. Risk factors include older age, male sex, severe cardiopulmonary disease, high ASA score, pulmonary hypertension, diuretic or warfarin use, osteoporosis, and malignancy.<br /><br />The presumed mechanism involves embolic release of medullary contents during cementation and/or inflammatory mediator release. BCIS is usually time-limited and often improves within 24 hours. Treatment is supportive: 100% oxygen, IV fluids, vasopressors if needed, and close hemodynamic monitoring.<br /><br />In this patient, oxygen needs and tachycardia gradually improved over several days, and she eventually had normal ambulatory oxygen saturation. The key takeaway is that BCIS should be considered in postoperative orthopedic patients with unexplained hypoxia and hypotension after cemented procedures.
Asset Subtitle
Saloni K. Maharaj
Meta Tag
Author List
Saloni K. Maharaj
Category
Clinical Vignettes
Concept
Bone Cement Implantation Syndrome
Concept
Postoperative Hypoxia
Concept
Hypoxia
Concept
Diagnosis of Exclusion
Concept
Supportive Care
Distinguished
Non-Finalist
Presenter Organization
Stanford University School of Medicine
Presenting Author
Saloni K. Maharaj
Track
Adult
Keywords
bone cement implantation syndrome
BCIS
postoperative hypoxia
hypotension
tachycardia
cemented total hip arthroplasty
femoral neck fracture
orthopedic surgery
pulmonary embolism exclusion
supportive treatment
Bone Cement Implantation Syndrome
Postoperative Hypoxia
Hypoxia
Diagnosis of Exclusion
Supportive Care
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