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Sepsis Squashing Squadron: Expediting Floor Sepsis ...
Sepsis Squashing Squadron: Expediting Floor Sepsis Recognition and Treatment
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The poster describes a pilot quality-improvement project called the “Sepsis Squashing Squadron” aimed at improving recognition and treatment of sepsis on general hospital floors. Because early antibiotics and prompt recognition are key to reducing sepsis mortality, the team built on an earlier Epic “sepsis score” alert by creating a multidisciplinary sepsis response process that combined manual chart review with automated electronic health record (EHR) scoring tools and summary displays.<br /><br />In the first pilot, a team member reviewed patients on one unit each morning. Patients with suspected infection and elevated SOFA or SIRS scores were assessed for compliance with SEP-1 bundle elements. If needed, the reviewer contacted the primary team and nursing staff with recommendations and offered extra support to complete tasks. The team also tested optimized combinations of Epic-derived scores to reduce unnecessary manual review.<br /><br />From May 16 to June 2, 2022, 190 patients were screened; 97 had probable or known infection. Only three patients required intervention for SEP-1 nonadherence. Average review time was 2 minutes per patient. Sepsis prevalence depended on the definition used, ranging from 5% with qSOFA to 24% with SOFA. Individual automated scores had limited performance for identifying floor sepsis: jMEWS was more sensitive but less specific, the Epic sepsis score was more specific but poorly sensitive, and the deterioration index was intermediate. A combined threshold using jMEWS, deterioration index, and/or SOFA improved screening performance to 93% sensitivity and 50% specificity.<br /><br />A second pilot in October–November 2022 screened 109 patients, found 11 SIRS-defined cases, and reduced average review time to 1 minute while maintaining 100% bundle adherence. Overall, the project suggests that combined EHR scores may streamline sepsis screening on general floors, but further refinement is needed.
Asset Subtitle
Mark Liotta
Meta Tag
Author List
Alan A. Kubey, Alyssa M. Yeager, Chantel Venkataraman, Christopher Haines, James Lee, Joy Burke, Kimberly Berenbaum, Mark Liotta, Nisreen Jahshan, Sara Groome
Category
Research
Concept
Sepsis
Concept
Early Antibiotic Administration
Concept
Centers for Medicare and Medicaid Services Severe Sepsis and Septic Shock Early Management Bundle
Concept
Sepsis Recognition
Concept
Sequential Organ Failure Assessment
Distinguished
Non-Finalist
Presenter Organization
Thomas Jefferson University Hospital
Presenting Author
Mark Liotta
Track
Quality Improvement
Keywords
sepsis
quality improvement
early recognition
antibiotic treatment
electronic health record
EHR scoring
SEP-1 bundle
SOFA score
SIRS criteria
hospital floors
Sepsis
Early Antibiotic Administration
Centers for Medicare and Medicaid Services Severe Sepsis and Septic Shock Early Management Bundle
Sepsis Recognition
Sequential Organ Failure Assessment
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