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Pregnancy-Associated Spontaneous Coronary Artery D ...
Pregnancy-Associated Spontaneous Coronary Artery Dissection: A Case Report and Comprehensive Discussion
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This case report describes a 22-year-old woman who developed spontaneous coronary artery dissection (SCAD) two weeks after delivering her first child. She presented with three days of intermittent sharp left-sided chest pain radiating to the left arm. Her vital signs were stable, but coronary angiography showed near-complete occlusion of the OM1 branch from the left circumflex artery, consistent with SCAD, while the remaining coronary arteries were normal.<br /><br />Because of the vessel’s small size and location, the team chose conservative management rather than stenting. Her chest pain resolved during hospitalization, and she was discharged the next day in stable condition. Although medications such as clopidogrel, atorvastatin, and a beta-blocker were initially considered, none were started because she was breastfeeding and had no history of atherosclerotic, hypertensive, or cardiac disease. At four-week follow-up, she remained symptom-free.<br /><br />The review highlights that SCAD is a non-traumatic, non-iatrogenic coronary artery wall separation that is especially common in women and can occur during pregnancy or the postpartum period. P-SCAD may account for up to 17% of SCAD cases. The condition causes intramural hematoma and compression of the true lumen, leading to myocardial ischemia. The most commonly affected artery is the left anterior descending artery, though any coronary vessel may be involved.<br /><br />Management is individualized. Heparin is stopped once SCAD is diagnosed, beta-blockers may reduce recurrence risk, and antiplatelet therapy is often used in non-PCI cases. Statin use remains controversial because SCAD is usually not caused by atherosclerosis. The authors emphasize maintaining a high index of suspicion for SCAD in young postpartum women with chest pain and tailoring treatment to breastfeeding status and other patient-specific factors.
Asset Subtitle
Jay Patel
Meta Tag
Author List
Anil Anumandla, Jay Patel, Paul Watanakunakorn, Samantha Limvalencia, Shiva Verma
Category
Clinical Vignettes
Concept
Spontaneous Coronary Artery Dissection
Concept
Intramural Hematoma
Concept
Pregnancy-Associated Spontaneous Coronary Artery Dissection
Concept
Type 4 SCAD
Concept
True Lumen Compression
Distinguished
Non-Finalist
Presenter Organization
Sierra View Medical Center
Presenting Author
Jay Patel
Track
Adult
Keywords
spontaneous coronary artery dissection
SCAD
postpartum
chest pain
young woman
coronary angiography
left circumflex artery
conservative management
breastfeeding
myocardial ischemia
Spontaneous Coronary Artery Dissection
Intramural Hematoma
Pregnancy-Associated Spontaneous Coronary Artery Dissection
Type 4 SCAD
True Lumen Compression
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