SHM Converge Scientific Abstract ePoster Gallery-Peripherally Inserted Central Catheters and Upper Extremity Deep Vein Thrombosis: Incidence and Risk Factors

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This retrospective matched cohort study examined the incidence of upper extremity deep venous thrombosis (DVT) in patients with peripherally inserted central catheters (PICCs) receiving outpatient parenteral antibiotic therapy. Records from 438 adults treated at a community hospital between 2017 and 2020 were reviewed. Patients had PICCs in place for 4–6 weeks, and DVT was confirmed by Doppler ultrasound. Those with superficial thrombosis or thrombosis at another site were excluded.<br /><br />Among the 438 patients, 24 developed DVT, giving a prevalence of 5.7%. The average age was 64.9 years, and the median time to DVT diagnosis was 21 days after PICC insertion. Age was not significantly associated with DVT risk.<br /><br />Univariable analysis showed that diabetes mellitus was the only comorbidity significantly associated with DVT, and it appeared protective: patients with diabetes were 72% less likely to develop DVT than those without diabetes (OR 0.28, 95% CI 0.08–0.79, P = 0.008). Other conditions, including hypertension, coronary artery disease, congestive heart failure, atrial fibrillation, chronic kidney disease, previous anticoagulation, prior DVT, and malignancy, were not significantly associated with DVT.<br /><br />The study concludes that PICC-associated upper extremity DVT occurred in a small but clinically important proportion of patients, usually within the first few weeks after insertion. Aside from a surprising inverse association with diabetes, no other major comorbidity was linked to increased risk in this sample.

Asset Subtitle

Osama Batayneh

Meta Tag

Author List David Rabinovich, Hadeel Zainah, Osama Batayneh, Ratib Mahfouz

Category Research

Concept Upper extremity deep vein thrombosis

Concept PICC Line

Concept Diabetes Mellitus

Concept Incidence

Concept Risk Factor

Distinguished Non-Finalist

Presenter Organization Kent Hospital/ Brown University

Presenting Author Osama Batayneh

Track Outcomes Research

Keywords

peripherally inserted central catheter

PICC

upper extremity deep venous thrombosis

outpatient parenteral antibiotic therapy

retrospective cohort study

Doppler ultrasound

diabetes mellitus

thrombosis prevalence

community hospital

venous thromboembolism

Upper extremity deep vein thrombosis

PICC Line

Diabetes Mellitus

Incidence

Risk Factor