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New Onset High-Output Heart Failure Post Renal Tra ...
New Onset High-Output Heart Failure Post Renal Transplant
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Pdf Summary
This case describes a 60-year-old man who developed new-onset high-output heart failure after a renal transplant. He presented with dyspnea, worsening edema, and 20 pounds of weight gain. Exam showed a palpable thrill over a right upper extremity arteriovenous fistula (AVF), and testing revealed mild renal dysfunction, elevated BNP, chest X-ray congestion, and echocardiographic evidence of pulmonary hypertension with preserved left ventricular function.<br /><br />Despite escalating diuretic therapy, his symptoms and kidney function did not improve significantly. Because of the persistent volume overload and the presence of the AVF, vascular ultrasound was performed and showed very high fistula flow, suggesting a high-output access. Ventilation-perfusion imaging was inconclusive for chronic thromboembolic pulmonary hypertension, so right heart catheterization was done to clarify the cause. It demonstrated markedly elevated cardiac output (Fick CO 13.1 L/min, CI 7.0 L/min/m²) with low pulmonary vascular resistance, supporting high-output heart failure rather than primary pulmonary vascular disease. Shunt study findings also supported mixing from the fistula.<br /><br />The patient then underwent surgical excision of the AVF aneurysm and ligation of the fistula. After surgery, his dyspnea and edema improved, renal function recovered, and repeat echocardiography showed reduced right ventricular systolic pressure from 43 mm Hg to 23 mm Hg.<br /><br />The key message is that AVFs can be an overlooked but important cause of high-output heart failure and pulmonary hypertension, especially in patients with renal disease or after transplant. Right heart catheterization was essential for diagnosis, and fistula ligation provided both diagnostic confirmation and effective treatment.
Asset Subtitle
Waleed Ikram
Meta Tag
Author List
Divya Shastri, Ibrahim Qaqish, Naomi Habib, Robert Lee, SAI-SRIDHAR Boddupalli, Saaed Nemr, Waleed Ikram
Category
Clinical Vignettes
Concept
Arteriovenous Fistula
Concept
High-Output Heart Failure
Concept
Fistula Ligation
Concept
Right Heart Catheterization
Concept
High-Flow Arteriovenous Fistula
Distinguished
Non-Finalist
Presenter Organization
Creighton University - Phoenix
Presenting Author
Waleed Ikram
Track
Adult
Keywords
high-output heart failure
renal transplant
arteriovenous fistula
pulmonary hypertension
right heart catheterization
volume overload
elevated cardiac output
fistula ligation
dyspnea
renal dysfunction
Arteriovenous Fistula
High-Output Heart Failure
Fistula Ligation
Right Heart Catheterization
High-Flow Arteriovenous Fistula
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