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Nationwide Analysis of the Impact of COVID-19 on E ...
Nationwide Analysis of the Impact of COVID-19 on ECMO Utilization in Patients Hospitalized With STEMI: A Retrospective Observational Study
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This retrospective national database study examined whether COVID-19 affected extracorporeal membrane oxygenation (ECMO) use among hospitalized patients with ST-segment-elevation myocardial infarction (STEMI) in the United States.<br /><br />Using Nationwide Inpatient Sample data from January to December 2020, the authors identified 198,335 STEMI hospitalizations after excluding patients under 18 and those with missing demographic data. Of these, 6,455 patients had concurrent COVID-19 and STEMI, while 191,880 had STEMI without COVID-19.<br /><br />Patients with STEMI and COVID-19 were more often female, Hispanic, African American, on Medicare, and from lower-income groups. ECMO use was more common in the raw comparison among STEMI patients with COVID-19 than those without COVID-19 (0.86% vs 0.07%). However, after adjusting for other factors in regression analysis, STEMI patients with COVID-19 had significantly lower odds of receiving ECMO than those without COVID-19 (OR 0.33, 95% CI 0.25–0.44, p<0.0001).<br /><br />Other factors associated with higher ECMO use included female sex, African American race, heart failure, and arrhythmias. The model showed strong predictive performance (AUC 0.929).<br /><br />The authors conclude that although ECMO may benefit some patients with severe COVID-19 and STEMI, real-world data suggest these patients are less likely to receive ECMO. They recommend further prospective studies to better evaluate ECMO’s role in severe COVID-19-associated STEMI and to help guide care.
Asset Subtitle
Nilay Bhatt
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Author List
Abdul Qadree, Aditya Thakkar, Bhanu Matri, Harsh Patel, Jose Davis, Maania Naseem, Nagaraj Honganur, Nilay Bhatt, Omar Hassan, Parth Shah, Payal Singh, Saketh Iswarawaka, Soumya Gupta, Urvish Patel, Yash Patel
Category
Research
Concept
STEMI
Concept
COVID-19
Concept
Extracorporeal Membrane Oxygenation
Concept
ECMO utilization rate
Concept
Hospitalization
Distinguished
Non-Finalist
Presenter Organization
HCA Houston Healthcare, Clear Lake, Texas
Presenting Author
Nilay Bhatt
Track
Outcomes Research
Keywords
COVID-19
STEMI
ECMO
hospitalized patients
Nationwide Inpatient Sample
retrospective study
extracorporeal membrane oxygenation
myocardial infarction
United States
regression analysis
STEMI
COVID-19
Extracorporeal Membrane Oxygenation
ECMO utilization rate
Hospitalization
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