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Missed in the Medication List: Fo-Ti Induced Hepat ...
Missed in the Medication List: Fo-Ti Induced Hepatitis Reveals a Diagnostic Gap
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Pdf Summary
This case highlights a 52-year-old woman who presented with several weeks of pruritus, dark urine, and scleral icterus, with markedly elevated liver enzymes and bilirubin consistent with severe hepatocellular injury. Initial workup for common causes of acute hepatitis was unrevealing, including negative infectious testing, unremarkable autoimmune evaluation, and negative imaging studies.<br /><br />The key diagnostic clue was later identification of daily Fo-Ti (He Shou Wu) use as an over-the-counter hair supplement for one year, which had been omitted from the medication list. After stopping Fo-Ti, her symptoms improved and liver tests normalized within six weeks, supporting herb-induced liver injury (HILI) as the cause.<br /><br />The report emphasizes that herbal supplements are commonly missed during medication reconciliation and should be specifically assessed in patients with unexplained transaminitis or jaundice. Fo-Ti is widely used for hair growth and anti-aging, especially among middle-aged women, but has been linked to hepatotoxicity. Risk may vary by product type, preparation method, anthraquinone content, and possibly genetic susceptibility.<br /><br />Overall, the case underscores the importance of routinely asking about nonprescription supplements in hospital and outpatient settings. Recognition of HILI depends on excluding other etiologies, identifying a temporal relationship between exposure and injury, and observing improvement after discontinuation.
Asset Subtitle
Chinmayi Sharma
Meta Tag
Author List
Chinmayi Sharma, Prashanth Bhat, Sahil Bangar, Samantha Gutierrez, Yash Patel, Zaheer Choudhury
Category
Clinical Vignettes
Concept
Herb-Induced Liver Injury
Concept
Fo-Ti
Concept
Herbal Supplement Use
Concept
Hepatotoxicity
Concept
Aminotransferase Elevation
Distinguished
Non-Finalist
Presenter Organization
Baptist Memorial Hospital
Presenting Author
Chinmayi Sharma
Track
Adult
Keywords
Fo-Ti
He Shou Wu
herb-induced liver injury
hepatotoxicity
jaundice
transaminitis
herbal supplements
pruritus
scleral icterus
medication reconciliation
Herb-Induced Liver Injury
Fo-Ti
Herbal Supplement Use
Hepatotoxicity
Aminotransferase Elevation
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