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Melanoma Mimicking a Diabetic Foot Infection
Melanoma Mimicking a Diabetic Foot Infection
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A 58-year-old man with type 2 diabetes, hypertension, peripheral arterial disease, and prior right fifth toe amputation for osteomyelitis presented with worsening pain at a chronic, non-healing right foot ulcer. The ulcer had originally been diagnosed as a diabetic foot infection two years earlier, but it persisted despite multiple antibiotic courses and improved glycemic control. He had also recently been hospitalized for ulcer management, including excisional debridement and anterior tibialis angioplasty.<br /><br />On presentation, he was tachycardic and had fluctuance around the plantar right foot ulcer. Examination also revealed a firm, tender right inguinal mass. Laboratory testing showed leukocytosis. Broad-spectrum antibiotics were started, but MRI demonstrated an enlarging 5 x 4 cm plantar soft tissue mass rather than a simple infection. He underwent wide local excision of the foot lesion with punch biopsies.<br /><br />Ultrasound of the inguinal mass suggested possible abscess, but it continued to enlarge despite IV antibiotics. Excisional biopsy of the inguinal lesion revealed metastatic malignant melanoma, matching the pathology from the right foot mass. This case illustrates how an apparent chronic diabetic foot ulcer that fails to heal despite appropriate treatment should raise concern for an underlying malignancy rather than persistent infection.
Asset Subtitle
Dennis P. Kurian
Meta Tag
Author List
Amanda BonanoCarambot, Dennis P. Kurian, Erica Grabscheid, Karishma Vijay Rupani, Maria Riasat
Category
Clinical Vignettes
Concept
Diabetic Foot Ulcer
Concept
Biopsy
Concept
Malignant Melanoma
Concept
Malignancy
Concept
Soft Tissue Mass
Distinguished
Non-Finalist
Presenter Organization
NYU Langone
Presenting Author
Dennis P. Kurian
Track
Adult
Keywords
diabetic foot ulcer
malignant melanoma
metastatic melanoma
chronic non-healing wound
soft tissue mass
foot infection
inguinal mass
biopsy
osteomyelitis
peripheral arterial disease
Diabetic Foot Ulcer
Biopsy
Malignant Melanoma
Malignancy
Soft Tissue Mass
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