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Medical Mistrust and Clinical Trial Participation
Medical Mistrust and Clinical Trial Participation
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This study examined medical mistrust and what motivates people to join cancer clinical trials, using data from the 2020 NCI Health Information National Trends Survey (HINTS). Medical mistrust was defined as reporting only “some,” “a little,” or “not at all” trust in cancer information from a doctor.<br /><br />Among 3,452 participants, 24% reported medical mistrust. Race was not an independent predictor of mistrust after adjustment, though financial distress was associated with higher mistrust. The study found that people with medical mistrust were less likely to be motivated by common factors such as altruism, expected clinical benefit, doctor encouragement, material support, and encouragement from family or friends.<br /><br />Overall, the findings suggest that usual incentives may be less effective for individuals who distrust the medical system. However, greater knowledge about clinical trials was linked to stronger motivation to participate. This implies that improving education and awareness about clinical trials may be a useful strategy for increasing participation, especially among underrepresented groups. The authors conclude that efforts to boost trial enrollment should focus not only on incentives, but also on building trust and increasing understanding of clinical trials.
Asset Subtitle
Shreeya Thussu
Meta Tag
Author List
Mark Fiala, Shreeya Thussu
Category
Research
Concept
Medical Mistrust
Concept
Cancer Clinical Trials
Concept
Participation
Concept
Clinical Trial Knowledge
Distinguished
Non-Finalist
Presenter Organization
Saint Louis University School of Medicine
Presenting Author
Shreeya Thussu
Track
Translating Research into Practice
Keywords
medical mistrust
cancer clinical trials
HINTS survey
trial participation
financial distress
trust in doctors
clinical trial knowledge
altruism
patient motivation
underrepresented groups
Medical Mistrust
Cancer Clinical Trials
Participation
Clinical Trial Knowledge
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