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Maintaining the Differential Diagnoses: Cardiopulm ...
Maintaining the Differential Diagnoses: Cardiopulmonary Compromise in the Preoperative Assessment
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This case highlights the importance of keeping a broad differential during preoperative assessment, especially in older patients with multimorbidity. A 67-year-old man with tobacco use, obesity, untreated obstructive sleep apnea, and recurrent basal cell carcinoma was evaluated before major head and neck surgery. Although he previously tolerated surgery, he now reported 1 month of worsening dyspnea on exertion, reduced exercise tolerance, and fatigue. Initial vitals were relatively stable, but exam and ECG raised concern, including new T-wave inversions and an old infarct pattern. Standard perioperative risk tools suggested low-to-moderate risk, yet clinical concern persisted.<br /><br />Further evaluation with transthoracic echocardiography showed mild right ventricular enlargement with reduced function, prompting cancellation of surgery and cardiology assessment. When symptoms worsened, he presented to the ED with hypoxemia, elevated NT-proBNP, mild troponin elevation, and chest imaging showing multifocal ground-glass opacities. Differential diagnoses included acute heart failure, pneumonia, pulmonary embolism, COPD exacerbation, metastatic disease, deconditioning, and NSTEMI.<br /><br />Definitive testing revealed bilateral pulmonary emboli with right heart strain on CT angiography and extensive left-leg deep vein thrombosis on duplex ultrasound. He was started on heparin, reviewed by the Pulmonary Embolism Response Team, and then transitioned to apixaban; thrombolysis was not indicated because he remained stable.<br /><br />Key takeaways: risk calculators are useful, but they do not replace clinical judgment. Preoperative evaluation should consider the whole patient, not just surgical risk scores. In patients with unexplained dyspnea or ECG findings suggestive of PE, clinicians should consider PE-specific tools such as Wells and PERC and pursue additional testing when warranted.
Asset Subtitle
Avital Y. O'Glasser
Meta Tag
Author List
Alexis Garcia, Avital Y. O'Glasser, Daniel Young, Elizabeth Hays, Howard Freeman, Mara Peterson, Ryan Kane
Category
Clinical Vignettes
Concept
Preoperative Assessment
Concept
Pulmonary Embolism
Concept
Clinical Context
Concept
Right Heart Strain
Concept
PE Risk Stratification
Distinguished
Non-Finalist
Presenter Organization
Oregon Health & Science University
Presenting Author
Avital Y. O'Glasser
Track
Adult
Keywords
preoperative assessment
pulmonary embolism
right heart strain
deep vein thrombosis
dyspnea on exertion
obstructive sleep apnea
ECG T-wave inversions
transthoracic echocardiography
perioperative risk
clinical judgment
Preoperative Assessment
Pulmonary Embolism
Clinical Context
Right Heart Strain
PE Risk Stratification
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