SHM Converge Scientific Abstract ePoster Gallery-Inhaled Bronchodilators: Novel Approach to Improved Outcomes in the Treatment of Pneumonia Requiring Hospitalization in Absence of Underlying Lung Disease?

Inhaled Bronchodilators: Novel Approach to Improved Outcomes in the Treatment of Pneumonia Requiring Hospitalization in Absence of Underlying Lung Disease?

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This retrospective multicenter cohort study examined whether inhaled bronchodilators improve outcomes in hospitalized patients with pneumonia who do not have known underlying lung disease (such as asthma or COPD). The study used data from 152 HCA Healthcare hospitals across 20 states and included patients hospitalized between January 1 and December 31, 2019.<br /><br />A total of 1,593 patients were analyzed, and 32.89% received an inhaled bronchodilator at least once within 24 hours of admission. The primary outcomes were hospital length of stay, ICU admission, and in-hospital mortality.<br /><br />Results showed that patients who received inhaled bronchodilators had a significantly shorter hospital stay, averaging 3.66 days less than those who did not receive them. They also had a lower rate of ICU admission. Patients who did not receive bronchodilators were more likely to require ICU care (OR 1.279, 95% CI 1.032–1.585; p=0.0244). However, there was no statistically significant difference in in-hospital mortality between the two groups.<br /><br />Overall, the authors concluded that inhaled bronchodilator use may be associated with improved clinical outcomes in hospitalized pneumonia patients without underlying lung disease, particularly by reducing length of stay and ICU admission. They suggest that bronchodilators may have a beneficial role in this population, though further research would be needed to confirm causation and guide routine use.

Asset Subtitle

Gabriella Muller

Meta Tag

Author List Dale L. Taylor, Gabriella Muller, Gerald Keller

Category Research

Concept Bronchodilator

Concept Hospital Length of Stay

Concept Pneumonia

Concept Intensive Care Unit Admission

Concept Inpatient Mortality

Distinguished Non-Finalist

Presenter Organization UCF HCA GME Consortium

Presenting Author Gabriella Muller

Track Outcomes Research

Keywords

pneumonia

inhaled bronchodilators

hospitalized patients

retrospective cohort study

multicenter study

length of stay

ICU admission

in-hospital mortality

lung disease

clinical outcomes

Bronchodilator

Hospital Length of Stay

Pneumonia

Intensive Care Unit Admission

Inpatient Mortality