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Hidden in Plain Sight
Hidden in Plain Sight
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Pdf Summary
This case describes a 74-year-old woman with urothelial cancer, atrial fibrillation on warfarin, hypertension, diabetes, and prior stroke who was hospitalized for suspected infected hydronephrosis. She underwent ureteral stent placement, received broad-spectrum antibiotics, and later was restarted on a heparin drip after anticoagulation had been temporarily held. During recovery, she developed ongoing crampy abdominal pain, poor appetite, constipation, intermittent tachycardia, and occasional hypotension. Initial abdominal evaluation was unrevealing, including a normal abdominal X-ray.<br /><br />By day 6, her pain persisted, her hemoglobin dropped significantly, and she developed abdominal tenderness with peritoneal signs and intermittent hypotension. Repeat CT imaging revealed a large rectus sheath hematoma and a large extraperitoneal hematoma, consistent with spontaneous bleeding related to anticoagulation.<br /><br />The discussion emphasizes that spontaneous rectus sheath and retroperitoneal hematomas are important complications of anticoagulation, particularly intravenous heparin. Risk factors include older age, female sex, diabetes, hypertension, malignancy, anemia, prior stroke, chronic kidney disease, and other bleeding risks. Typical presentation includes abdominal pain, abdominal swelling or mass, hypotension, tachycardia, and falling hemoglobin.<br /><br />Management is usually conservative and includes stopping or reversing anticoagulation, transfusion support, and close hemodynamic monitoring. In selected cases, interventional radiology or surgery may be needed for embolization or further control of bleeding.<br /><br />The key lesson is that persistent postoperative abdominal pain in patients receiving anticoagulation should prompt a high index of suspicion for occult bleeding, even when early imaging is normal. In this patient, holding heparin, transfusing blood, and monitoring closely led to improvement, and anticoagulation was later restarted without further bleeding.
Asset Subtitle
Radha Devi Radhakrishna Pillai
Meta Tag
Author List
Nathan Martin, Radha Devi Radhakrishna Pillai
Category
Clinical Vignettes
Concept
Heparin
Concept
Rectus Sheath Hematoma
Concept
Extraperitoneal Hematoma
Concept
Abdominal Pain
Concept
Hemoglobin
Distinguished
Non-Finalist
Presenter Organization
Washington University School of Medicine
Presenting Author
Radha Devi Radhakrishna Pillai
Track
Adult
Keywords
urothelial cancer
atrial fibrillation
warfarin
heparin anticoagulation
infected hydronephrosis
ureteral stent
rectus sheath hematoma
retroperitoneal hematoma
abdominal pain
occult bleeding
Heparin
Rectus Sheath Hematoma
Extraperitoneal Hematoma
Abdominal Pain
Hemoglobin
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