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Hemophagocytic Lymphohistiocytosis Due to Previous ...
Hemophagocytic Lymphohistiocytosis Due to Previous Sars-Cov-2 Infection
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Pdf Summary
The document describes a case of hemophagocytic lymphohistiocytosis (HLH) associated with COVID-19. It highlights how HLH and severe COVID-19 can look similar, which may delay diagnosis. In this case, an elevated ferritin level led to further testing and the diagnosis of HLH. Additional workup found no infectious or malignancy-related cause. <br /><br />The patient was treated with steroids and improved immediately. The discussion emphasizes that HLH should be considered in patients with current or recent COVID-19 infection who continue to have symptoms or develop multi-organ failure. <br /><br />The document also includes an HScore evaluation, which is used to estimate the likelihood of HLH. It notes that an HScore of 169 has high diagnostic sensitivity and specificity for HLH, and the patient’s total score was reported as 244, strongly supporting the diagnosis.
Asset Subtitle
Madison L. Paul
Meta Tag
Author List
Alejandro Chapa-Rodriquez, Madison L. Paul, Puranchander R. Vangala, Ryan Coffey
Category
Clinical Vignettes
Concept
Hemophagocytic Lymphohistiocytosis
Concept
H-score
Concept
Severe COVID-19
Concept
Ferritin
Concept
Steroid Treatment
Distinguished
Non-Finalist
Presenter Organization
Madigan Family Medicine Residency/Joint Base Lewis McChord/Us Army
Presenting Author
Madison L. Paul
Track
Adult
Keywords
hemophagocytic lymphohistiocytosis
HLH
COVID-19
ferritin
HScore
multi-organ failure
steroids
diagnosis
hyperinflammation
case report
Hemophagocytic Lymphohistiocytosis
H-score
Severe COVID-19
Ferritin
Steroid Treatment
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