SHM Converge Scientific Abstract ePoster Gallery-Gender Disparities in Clinical Outcomes of Acute Pancreatitis: A National Cohort Analysis

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This poster reports a nationwide retrospective analysis of acute pancreatitis (AP) outcomes in males versus females using the 2020 Nationwide Inpatient Sample (NIS) database and ICD-10 codes. The study included 252,595 adult hospitalizations for AP, with a mean age of 50.9 years; 55.1% were male and the majority were White (63.64%).<br /><br />The primary outcome was in-hospital mortality, and secondary outcomes included length of stay (LOS), hospitalization charges, acute kidney injury (AKI), sepsis, shock, and ICU admission. Multivariate logistic regression was used to adjust for confounders and determine whether sex was an independent predictor of outcomes.<br /><br />Female patients had a higher prevalence of congestive heart failure, chronic kidney disease, and obesity, while males had more type 2 diabetes. After adjustment, females had significantly better inpatient outcomes than males, including lower odds of in-hospital mortality (aOR 0.64), AKI (aOR 0.72), sepsis (aOR 0.68), and shock (aOR 0.74). These findings indicate that females had 36% lower odds of death, 28% lower odds of AKI, 32% lower odds of sepsis, and 26% lower odds of shock compared with males.<br /><br />There were no statistically significant sex-based differences in LOS, total hospitalization charges, or ICU admission rates.<br /><br />Overall, the study concludes that female patients hospitalized with acute pancreatitis experience significantly better clinical outcomes than male patients. The authors suggest that further prospective research is needed to better understand the reasons for these differences and to inform clinical practice.

Asset Subtitle

Ahmed Ali Aziz

Meta Tag

Author List Ahmed Ali Aziz, Ijlal Akbar Ali, Muhammad Ali Aziz, Muhammad Amir, Rehan Shah, Rida Zahid, Sara Rahman, Syed Taseen

Category Research

Concept Retrospective Comparative Outcomes Study

Concept Acute Pancreatitis

Concept HCUP-NIS

Concept Inpatient Outcomes

Concept Mortality

Distinguished Non-Finalist

Presenter Organization INTEGRIS Health Baptist Medical Center, Oklahoma City, Oklahoma & Oklahoma State University College of Osteopathic Medicine, Stillwater, Oklahoma

Presenting Author Ahmed Ali Aziz

Track Outcomes Research

Keywords

acute pancreatitis

sex differences

female outcomes

male outcomes

nationwide inpatient sample

retrospective analysis

in-hospital mortality

acute kidney injury

sepsis

hospitalization outcomes

Retrospective Comparative Outcomes Study

Acute Pancreatitis

HCUP-NIS

Inpatient Outcomes

Mortality