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Fever in the Returning Traveler: Dengue in Wiscons ...
Fever in the Returning Traveler: Dengue in Wisconsin and the Indispensability of a Sage H&p
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This case describes a 58-year-old man who returned from a 14-day trip to the Philippines and developed fever, nausea, diarrhea, retro-orbital pain, and a diffuse erythematous rash within 48 hours. He had eaten at street markets, stayed in a beachside village north of Manila, and did not use mosquito precautions. On exam, he had orbital pain with extraocular movements and a blanchable rash with areas of pallor on the chest and upper extremities.<br /><br />Initial labs showed neutropenia and thrombocytopenia, raising concern for tick-borne illness or viral hemorrhagic fever. An extensive infectious workup was negative, including testing for anaplasmosis, ehrlichiosis, babesiosis, Lyme disease, chikungunya, malaria, leptospirosis, EBV, HIV, hepatitis A/B, CMV, and GI/respiratory panels. Dengue fever was confirmed by a positive serum IgM antibody.<br /><br />The patient was treated supportively with IV fluids and acetaminophen, improved without complications, and was discharged after receiving empiric doxycycline. The presentation highlights the importance of considering dengue in febrile returning travelers, especially after travel to endemic regions in Southeast Asia.<br /><br />The accompanying discussion emphasizes WHO dengue classification and clinical recognition. Dengue is transmitted by Aedes mosquitoes and typically has a 3–14 day incubation period. Common features include fever, retro-orbital pain, vomiting, myalgia, rash, thrombocytopenia, and sometimes hemorrhagic signs or plasma leakage in the critical phase. The article stresses the need for careful history-taking, risk stratification, and timely diagnosis to distinguish dengue from other causes of fever in travelers.
Asset Subtitle
Alexander W. Nelson
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Author List
Alexander W. Nelson
Category
Clinical Vignettes
Concept
Dengue Fever
Concept
Fever
Concept
WHO Dengue Classification
Concept
Supportive Care
Concept
Severe Dengue
Distinguished
Non-Finalist
Presenter Organization
University of Wisconsin School of Medicine and Public Health
Presenting Author
Alexander W. Nelson
Track
Adult
Keywords
dengue fever
returning traveler
Philippines travel
retro-orbital pain
thrombocytopenia
neutropenia
Aedes mosquito
febrile rash
Southeast Asia
dengue IgM
Dengue Fever
Fever
WHO Dengue Classification
Supportive Care
Severe Dengue
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