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Evaluating the Safety of Avoiding Lumbar Punctures ...
Evaluating the Safety of Avoiding Lumbar Punctures in Febrile Infants
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Pdf Summary
This retrospective study evaluated whether lumbar punctures (LPs) can be safely avoided in low-risk febrile infants aged 7–28 days using a clinical pathway introduced in 2018. The goal was to reduce unnecessary invasive procedures while still detecting bacterial meningitis, a serious but uncommon condition.<br /><br />Researchers reviewed ED visits from 2018–2022 for full-term infants with fever who were managed on the pathway. Infants who were ill-appearing, had focal infection, or seizures were excluded. Low-risk status was based on clinical history, CBC, procalcitonin, urinalysis, and culture results. Low-risk infants did not require LPs or antibiotics under the protocol.<br /><br />A total of 385 infants met inclusion criteria. Of these, 166 (43%) were classified as low-risk and 219 (57%) as high-risk. The mean age of low-risk infants was 19.5 days. Among the 166 low-risk infants, 140 (84%) did not undergo LPs as recommended. Importantly, there were no missed cases of bacterial meningitis in these infants. The 26 low-risk infants who still received LPs did so for reasons such as prior LP at another hospital, clinician judgment, positive cultures after admission, increased fussiness, or seizures after admission. None had bacterial meningitis, though one had viral meningitis.<br /><br />The study concluded that LPs can be safely avoided in low-risk febrile infants 7–28 days without missed bacterial meningitis cases.
Asset Subtitle
Ammar Kamil
Meta Tag
Author List
Ammar Kamil, Hannah Riggins, Jamie Librizzi, Maheshwor Kafle
Category
Research
Concept
Risk Stratification
Concept
Febrile Infant
Concept
Lumbar Puncture
Concept
Infant Age 728 Days
Concept
Invasive Bacterial Infection
Distinguished
Non-Finalist
Presenter Organization
Phoenix Children's Hospital
Presenting Author
Ammar Kamil
Track
Pediatric
Keywords
lumbar puncture
febrile infants
bacterial meningitis
low-risk pathway
retrospective study
clinical protocol
neonatal fever
emergency department
procalcitonin
invasive procedures
Risk Stratification
Febrile Infant
Lumbar Puncture
Infant Age 728 Days
Invasive Bacterial Infection
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