SHM Converge Scientific Abstract ePoster Gallery-Evaluating the Impact of Gabapentin on Older Adult Trauma Patients' Outcomes

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This retrospective cohort study from Mayo Clinic Rochester examined whether gabapentin use affected outcomes in older adult trauma patients (age 65+) admitted between May 2018 and May 2023. Data were drawn from the TraumaBase V9 registry and Mayo Data Explorer, and analyzed with Python and SAS 9.4.<br /><br />The study evaluated associations between gabapentin and several clinical outcomes: pain, opioid use, delirium, ICU stay, and mortality. Univariable and multivariable linear and logistic regression models were used, adjusting for important confounders such as age, injury severity score (ISS), rib fracture, COPD, and length of stay. Because pain and opioid data were skewed, they were analyzed both in raw form and after inverse normal transformation. Additional models treated gabapentin dose as a continuous variable.<br /><br />The background emphasizes that gabapentin is commonly used as part of multimodal pain control, especially in trauma and perioperative care, but it should be used cautiously in older adults, particularly those with comorbidities or respiratory compromise.<br /><br />Overall, the study aimed to determine whether gabapentin was linked to delirium risk and whether it improved pain control or reduced opioid use in older trauma patients. The conclusion notes that gabapentin remains a useful component of multimodal analgesia in this population, but its use should be individualized based on clinical context, patient-specific factors, and awareness of risks associated with longer-term or outpatient prescribing.

Asset Subtitle

Mohamad K. Abou Chaar

Meta Tag

Author List Bradley J. Peters, Chun Fan, Corrie A. Kangas, Mohamad K. Abou Chaar, Nital Vaghela, Robert A. Vierkant, Sandeep R. Pagali, Veljko Strajina

Category Research

Concept Gabapentin

Concept Older Adult Trauma Patients

Concept Clinical Outcome

Concept Pain

Concept Opioid Use

Distinguished Non-Finalist

Presenter Organization Division of Trauma, Critical Care, and General Surgery, Department of Surgery, Mayo Clinic, Rochester, MN

Presenting Author Mohamad K. Abou Chaar

Track Geriatrics

Keywords

gabapentin

older adult trauma

multimodal analgesia

delirium risk

opioid use

pain control

retrospective cohort study

Mayo Clinic Rochester

injury severity score

ICU stay

Gabapentin

Older Adult Trauma Patients

Clinical Outcome

Pain

Opioid Use