SHM Converge Scientific Abstract ePoster Gallery-Epidemiology of Non-Variceal Upper Gastrointestinal Bleeding in Patients With Cirrohosis

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This population-based retrospective study examined non-variceal upper gastrointestinal bleeding (NVUGIB) among cirrhotic patients using the U.S. National Inpatient Sample from 2007–2018. The authors analyzed 9,804,819 cirrhosis-related hospitalizations and identified 160,194 NVUGIB admissions (1.6%). The overall hospitalization trend remained stable over time, decreasing only slightly from 2.0% in 2007 to 1.7% in 2018, with no significant trend.<br /><br />Patients hospitalized with NVUGIB were slightly younger than other cirrhotic inpatients (57 vs. 59 years) and more often male (64%). In multivariable analysis, higher odds of NVUGIB were associated with older age, male sex, residence in the Western U.S., Helicobacter pylori infection, and alcoholism. Other factors linked to increased NVUGIB hospitalization included hypertension, valvular heart disease, NSAID use, and smoking. Several of these are potentially modifiable risk factors.<br /><br />The study also found important adverse outcomes. Among cirrhotic patients admitted with NVUGIB, 14.7% required discharge to a facility, 5.0% died during hospitalization, and the average length of stay was 6 days.<br /><br />Overall, the study demonstrates that NVUGIB is a significant and persistent cause of hospitalization in cirrhotic patients and is associated with substantial morbidity and mortality. The findings highlight the need for further research to identify causal mechanisms and develop preventive strategies in this high-risk population.

Asset Subtitle

Vrushali Shelar

Meta Tag

Author List Achint Patel, Hardik Shah, Kingsley Agbodike, Mohammad Syam, Momna Wazir, Parinitha Prasad, Suchitra Lawanya, Tsu Jung Yang, Vrushali Shelar, Yohannes Mengistu

Category Research

Concept Non-Variceal Upper Gastrointestinal Bleeding

Concept Cirrhosis

Concept Epidemiology

Concept Hospitalization

Concept Helicobacter pylori Infection

Distinguished Non-Finalist

Presenter Organization Saratov State Medical University, Russia

Presenting Author Vrushali Shelar

Track Outcomes Research

Keywords

non-variceal upper gastrointestinal bleeding

cirrhosis

hospitalization trends

risk factors

Helicobacter pylori

alcoholism

NSAID use

smoking

mortality

morbidity

Non-Variceal Upper Gastrointestinal Bleeding

Cirrhosis

Epidemiology

Hospitalization

Helicobacter pylori Infection