SHM Converge Scientific Abstract ePoster Gallery-Epidemiology and Socio-Demographic Disparity Associated With Takayasu Arteritis

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This nationwide retrospective cross-sectional study used the US National Inpatient Sample database (2016–2018) to examine the prevalence and association of cerebrovascular events in patients with Takayasu arteritis (TA), a chronic large-vessel vasculitis affecting the aorta and its branches.<br /><br />Among 3,560 TA patients, the condition was more common in younger adults (18–50 years), females, Hispanic patients, and Asian/Pacific Islander patients compared with non-TA hospitalizations. TA patients also had higher rates of major cerebrovascular events, including acute ischemic stroke (2.53% vs. 1.73%), transient ischemic attack (1.4% vs. 0.36%), intracerebral hemorrhage (0.56% vs. 0.24%), and subarachnoid hemorrhage (0.14% vs. 0.08%), all statistically significant.<br /><br />Traditional vascular risk factors were also more frequent in the TA group, including hypertension, dyslipidemia, ischemic heart disease, and congestive heart failure. In multivariable regression analysis, transient ischemic attack, subarachnoid hemorrhage, acute ischemic stroke, and myocardial infarction were significantly associated with higher odds of TA.<br /><br />The authors conclude that TA is linked to a greater burden of cerebrovascular disease in the US inpatient population. They suggest that vascular inflammation, stenosis, and occlusion from TA may contribute to stroke risk. Because studies on this topic are limited, the authors recommend further prospective research to improve early identification and reduce cerebrovascular complications in patients with Takayasu arteritis.

Asset Subtitle

Ashima Gupta

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Author List Ashima Gupta, Barath Prashanth Sivasubramanian, Farahnaz Noei, Johnnie Saifa-Bonsu, Lokesh Manjani, Mihir Dave, Nagaraj Honganur, Pratikkumar Vekaria, Priya Savani, Richa Jaiswal, Srujana Konka, Tenzin Tamdin, Umabalan Terpari, Urvish Patel, Vikramad

Category Research

Concept Takayasu Arteritis

Concept Cerebrovascular Event

Concept Abdominal Aorta

Concept Acute Ischemic Stroke

Concept Arterial Branches

Distinguished Non-Finalist

Presenter Organization Dr. Panjabrao Deshmukh Memorial Medical College

Presenting Author Ashima Gupta

Track Education

Keywords

Takayasu arteritis

cerebrovascular events

acute ischemic stroke

transient ischemic attack

intracerebral hemorrhage

subarachnoid hemorrhage

National Inpatient Sample

large-vessel vasculitis

vascular risk factors

stroke risk

Takayasu Arteritis

Cerebrovascular Event

Abdominal Aorta

Acute Ischemic Stroke

Arterial Branches