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Development and Piloting of a Real-Time Ehr-Based ...
Development and Piloting of a Real-Time Ehr-Based Predictive Algorithm for Diagnostic Error
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This study developed and piloted a real-time electronic health record (EHR)-based predictive algorithm to estimate a patient’s risk of diagnostic error (DE) during hospitalization. The goal was to improve clinician awareness of diagnostic uncertainty and encourage use of a “Diagnostic Time-Out” (DTO) when risk was elevated.<br /><br />The algorithm used baseline and dynamic EHR risk factors identified from literature and expert opinion, such as altered mental status, language barriers, inter-hospital transfer, multiple consultants, early readmission, recent ED visits, team changes, and increased oxygen needs. Patients were assigned a score that mapped to low (green), moderate (yellow), or high (red) DE risk flags in an EHR dashboard.<br /><br />To test whether clinicians found the risk flags meaningful, the team sent weekly yes/no polls to care team members for randomly selected general medicine patients. Clinicians were asked whether they would take a DTO for the patient. Of 99 patients polled (393 total polls), at least one response was received for 43 patients (43%). “Yes” responses increased with predicted risk: 7% for low-risk cases, 25% for moderate-risk cases, and 54% for high-risk cases. High-risk diagnoses such as altered mental status were significantly associated with “Yes” responses. When moderate or high-risk flags were used to predict a “Yes” response, the algorithm showed high sensitivity (92%) but low specificity (42%).<br /><br />Overall, the findings suggest clinicians were more likely to agree to a DTO as predicted DE risk increased, indicating the algorithm may help identify cases where diagnostic reflection is needed. Next steps include comparing predicted risk with actual chart-reviewed DE outcomes and refining the algorithm using larger datasets and adjudicated outcomes.
Asset Subtitle
Anuj K. Dalal
Meta Tag
Author List
Alyssa Lam, Anuj K. Dalal, Daniel Motta-Calderon, Jeffrey L. Schnipper, Kevin Carr, Pamela Garabedian, Savanna Plombon
Category
Innovations
Concept
Prediction Algorithm
Concept
Diagnostic Error
Concept
Patient Risk
Concept
Risk Factor
Concept
Perioperative Mortality Risk Prediction Tool
Distinguished
Non-Finalist
Presenter Organization
Brigham and Women's Hospital
Presenter Organization
Harvard Medical School
Presenting Author
Anuj K. Dalal
Track
Technology in Hospital Medicine
Keywords
diagnostic error
predictive algorithm
electronic health record
hospitalization
diagnostic time-out
clinical decision support
risk stratification
diagnostic uncertainty
altered mental status
real-time dashboard
Prediction Algorithm
Diagnostic Error
Patient Risk
Risk Factor
Perioperative Mortality Risk Prediction Tool
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