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Deimplementing Deliriogenic Drug Dosing Defaults: ...
Deimplementing Deliriogenic Drug Dosing Defaults: Exploring the Feasibility of Adjusting Ehr Default Dosing Schedules to Reduce Overnight Disruptions
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This project explored whether changing default medication dosing times in the electronic health record could reduce both nursing workload and overnight patient sleep disruption in 11 hospitals.<br /><br />Researchers exported all standing medication doses from June 2025, excluding PRN and one-time orders, leaving 253,597 doses for analysis. In the current state, medication administration occurred during 11 possible med-pass times across the day. This created a heavy burden on day nurses, who handled 7 med passes compared with 4 for night nurses, and 74% of administrations fell to the day shift. Although 75% of doses were given during key times like breakfast, lunch, dinner, evening, and bedtime, 4.9% still occurred during sleep time, defined as 10 p.m. to 6 a.m.<br /><br />The team tested several alternative default schedules, including two AI-generated options and one human-designed option. The human-designed version performed best across all measures. Proposed changes shifted common frequencies such as daily, BID, q8h, q12h, TID, q6h, and QID to more patient-friendly times. Under the projected future state, the number of administration hours would drop from 11 to 8, day nurse med passes would decrease from 7 to 4, and administration would become more evenly distributed between day and night staff. Consolidation during key times would improve from 75% to 87%, and sleep-time dosing would fall from 4.9% to 2.2%, representing about 82,000 fewer overnight doses per year across the 11 hospitals.<br /><br />The authors conclude that optimizing default dosing times can reduce nursing burden while substantially decreasing unnecessary overnight disruptions, and they are working toward EHR implementation.
Asset Subtitle
Alan Kubey
Meta Tag
Author List
Alan Kubey, Cara Martino, Charlene Eltman, Jeffrey Riggio
Category
Innovations
Concept
Medication Dosing Time
Concept
Medication Administration
Concept
Sleep Disruption
Concept
Electronic Health Record
Concept
Medication Frequency
Distinguished
Non-Finalist
Presenter Organization
Thomas Jefferson University and Mayo Clinic
Presenting Author
Alan Kubey
Track
Quality Improvement
Keywords
electronic health record
medication dosing times
nursing workload
overnight sleep disruption
hospital medication administration
default dosing schedule
day nurse med passes
sleep-time dosing
EHR optimization
patient-friendly dosing
Medication Dosing Time
Medication Administration
Sleep Disruption
Electronic Health Record
Medication Frequency
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