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Defying the Odds: Effective CPR Achieves Remarkabl ...
Defying the Odds: Effective CPR Achieves Remarkable Neurologic Preservation After Prolonged Cardiac Arrest
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This case report describes a 45-year-old woman with multiple sclerosis and morbid obesity (BMI 53) who developed dyspnea after immunotherapy and was found to have bilateral lower lobe pulmonary emboli plus a saddle embolus with right heart strain. She underwent suction thrombectomy but then suffered a pulseless electrical activity arrest.<br /><br />Manual CPR was started immediately, and she was intubated 12 minutes later. Because of her body habitus, robotic/mechanical compressions could not be used. Despite prolonged resuscitation, including transient return of spontaneous circulation episodes, she achieved full ROSC after 70 minutes. During the code, she received 13 doses of epinephrine and 4 doses of sodium bicarbonate.<br /><br />Her hospital course was complicated by renal deterioration requiring hemodialysis, but she stabilized hemodynamically after five days. Remarkably, she regained cognitive function and full motor ability within 10 days and was discharged after 28 days.<br /><br />The report emphasizes that high-quality CPR can lead to excellent neurologic outcomes even after very prolonged cardiac arrest, challenging assumptions that extended resuscitation is futile. It reinforces strict adherence to CPR guidelines: compressions at least 2 inches deep, 100 to 120 per minute, full chest recoil, minimal interruptions, pulse checks every 2 minutes, and the standard 30:2 ratio with proper airway maneuvers.<br /><br />The discussion notes that while evidence suggests neurologic outcomes generally decline with longer CPR duration, this case shows that favorable recovery is still possible when CPR is effective and persistent. The authors call for ongoing training and future studies to identify predictors of good neurologic recovery and to evaluate the role of mechanical compression devices.
Asset Subtitle
Joshua Tsai
Meta Tag
Author List
Hemantkumar Raval, Joshua Tsai, Juan Carlos Rivera-Martinez, Mason Grimm, Sophia Elortegui
Category
Clinical Vignettes
Concept
Cardiopulmonary Resuscitation
Concept
Chest Compression
Concept
Pulmonary Embolism
Concept
Neurologic Recovery
Concept
Neurological Function
Distinguished
Non-Finalist
Presenter Organization
Lakeland Regional Health
Presenting Author
Joshua Tsai
Track
Adult
Keywords
pulmonary embolism
saddle embolus
pulseless electrical activity
cardiopulmonary resuscitation
manual CPR
right heart strain
suction thrombectomy
morbid obesity
neurologic recovery
mechanical chest compressions
Cardiopulmonary Resuscitation
Chest Compression
Pulmonary Embolism
Neurologic Recovery
Neurological Function
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