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Cease and De-Cyst: Coordinating Care in Extensive ...
Cease and De-Cyst: Coordinating Care in Extensive Hydatid Disease
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A 34-year-old man from Afghanistan, who had immigrated from Pakistan two years earlier, presented with three months of right upper quadrant pain, bloating, and exertional dyspnea, along with edema and scrotal swelling. He reported a history of prior “cysts” after exposure to contaminated water in an endemic setting, and had undergone liver and lung surgeries about 10 years earlier without receiving anti-parasitic treatment.<br /><br />Laboratory tests showed cholestatic liver abnormalities and low albumin. Imaging revealed a large right posterior-inferior mediastinal fluid collection, additional cystic collections near the right costophrenic angle, ascites, and cardiac compression with both atria compressed by a cyst. Given the patient’s epidemiologic risk, prior surgeries, and imaging findings, hydatid disease from Echinococcus granulosus was strongly suspected. Echinococcus IgG later returned positive.<br /><br />He underwent right thoracotomy with cystotomy, capitonnage, and cystectomy of a mediastinal hydatid cyst. Albendazole was started 24 hours before surgery, and postoperative praziquantel was given to reduce the risk of anaphylaxis or dissemination if cyst contents spilled. Cultures and ova/parasite studies were negative, but pathology confirmed echinococcal cyst wall with germinal layer and protoscolices. Additional staged hepatobiliary surgery was planned for remaining abdominal and subdiaphragmatic cysts.<br /><br />The case highlights how recurrent hydatid disease can result from incomplete prior treatment and the importance of detailed history-taking, immigration and exposure assessment, and multidisciplinary coordination among hospital medicine, infectious disease, thoracic surgery, and hepatobiliary surgery. It also illustrates that management must be individualized when guidelines are inconsistent, especially in urgent cases with major cardiopulmonary compromise and high operative risk.
Asset Subtitle
Kyle James
Meta Tag
Author List
Brian Douglass, Daniel J. Gromer, Eszter Toth, Henry Wu, Kyle James, Laurence Balter, Matthew Collins, Puja Sasankan
Category
Clinical Vignettes
Concept
Hepatic Echinococcosis
Concept
Echinococcus granulosus
Concept
Clinical Presentation
Concept
Imaging Finding
Concept
Diagnostic Testing
Distinguished
Non-Finalist
Presenter Organization
Emory University Hospital Midtown
Presenting Author
Kyle James
Track
Adult
Keywords
hydatid disease
Echinococcus granulosus
mediastinal cyst
thoracotomy
albendazole
praziquantel
echinococcal cyst
immigration history
cardiac compression
multidisciplinary management
Hepatic Echinococcosis
Echinococcus granulosus
Clinical Presentation
Imaging Finding
Diagnostic Testing
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