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Breaking It Down - Spin Class Induced Rhabdomyolys ...
Breaking It Down - Spin Class Induced Rhabdomyolysis in a Healthy Young Adult
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This case describes a 21-year-old healthy woman who developed spin class–induced rhabdomyolysis after a high-intensity cycling workout. She presented with 5 days of bilateral thigh pain, worsening soreness, difficulty walking, lower abdominal pain, and 1 day of dark urine. She was initially treated at urgent care for a presumed UTI after urinalysis showed blood and protein, but her symptoms worsened and she came to the emergency center.<br /><br />On exam, she was tachycardic and had tenderness over both quadriceps and the lower abdomen, but no clear signs of compartment syndrome. Labs were diagnostic for severe rhabdomyolysis: creatine kinase (CK) was 100,000 U/L, with elevated AST and ALT, but normal kidney function. Urinalysis showed blood, protein, and mild pyuria, which can occur with myoglobinuria. Ultrasound ruled out DVT and abdominal pathology.<br /><br />She was treated primarily with aggressive IV fluid resuscitation: 3 liters of normal saline followed by maintenance fluids, with a goal of urine output around 200–300 mL/hour. Her CK improved rapidly, symptoms lessened, and surgery evaluated her when leg swelling increased, but compartment syndrome was excluded. IV fluids were later stopped as CK downtrended, and she was discharged with oral hydration and follow-up. Her CK, liver enzymes, and metabolic panel normalized on outpatient testing.<br /><br />The case highlights that exercise-induced rhabdomyolysis is increasingly seen in group fitness settings like spin classes, especially among beginners without conditioning. Early recognition is important to prevent complications such as acute kidney injury, liver enzyme elevation, arrhythmias, and compartment syndrome. Patients with recurrent episodes or severe cramping should be considered for genetic or metabolic myopathy testing.
Asset Subtitle
Anna K. Young
Meta Tag
Author List
Aaron Pathak, Anna K. Young, Doris Lin, Ifeanyi Anyaoha
Category
Clinical Vignettes
Concept
Rhabdomyolysis
Concept
Exercise-Induced Muscle Breakdown
Concept
Creatine Kinase
Concept
Acute Kidney Injury
Concept
Fluid Resuscitation
Distinguished
Non-Finalist
Presenter Organization
Baylor College of Medicine
Presenting Author
Anna K. Young
Track
Adult
Keywords
rhabdomyolysis
spin class
high-intensity exercise
creatine kinase
myoglobinuria
dark urine
quadriceps pain
intravenous fluids
acute kidney injury
compartment syndrome
Rhabdomyolysis
Exercise-Induced Muscle Breakdown
Creatine Kinase
Acute Kidney Injury
Fluid Resuscitation
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