SHM Converge Scientific Abstract ePoster Gallery-Boosting Counts, Breaking Skin: A Rare Case of Pyoderma Gangrenosum After Pegfilgrastim

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This poster template from PosterPresentations.com is a quick-start guide for creating a 36" x 48" research poster in PowerPoint. It explains how to adjust zoom, use headers and text boxes, add and resize photos, check image quality, switch column layouts, delete the built-in guide elements, preview the poster in slideshow mode, and print through the website. It also notes that the template can be printed in several other sizes without distortion.<br /><br />The included research case describes a 65-year-old woman with metastatic left invasive breast cancer who had undergone left mastectomy and was receiving chemotherapy. She developed two months of progressively worsening left lower extremity pain and a non-healing wound. Imaging showed a skin defect and inflammatory changes in the lower leg, while inflammatory markers were elevated and blood cultures were negative.<br /><br />She was diagnosed with drug-induced pyoderma gangrenosum (PG) attributed to pegfilgrastim. The case notes that PG is a rare neutrophilic dermatosis that often presents as rapidly progressive, very painful ulcers with violaceous borders and may follow a pustule or nodule. Her wounds improved after treatment with prednisone taper, clobetasol, dapsone, and doxycycline, and chemotherapy continued without pegfilgrastim.<br /><br />The conclusion emphasizes that drug-induced PG is rare but should be considered when ulcerative lesions develop after colony-stimulating factor therapy. Early recognition, stopping the suspected trigger when possible, immunosuppressive treatment, and wound care can lead to good outcomes.

Asset Subtitle

Tina C. Phan

Meta Tag

Author List Misha Rosenbach, Ogechi Ezemma Siaw, Robert Micheletti, Ronald Berna, Tina C. Phan

Category Clinical Vignettes

Concept Pyoderma Gangrenosum

Concept Ulcer

Concept Violaceous Border

Concept Pathergy

Concept Neutrophilic Dermatosis

Distinguished Non-Finalist

Presenter Organization University of Pennsylvania/Children's Hospital of Philadelphia

Presenting Author Tina C. Phan

Track Adult

Keywords

research poster

PowerPoint template

PosterPresentations.com

drug-induced pyoderma gangrenosum

pegfilgrastim

metastatic breast cancer

non-healing wound

neutrophilic dermatosis

colony-stimulating factor

immunosuppressive treatment

Pyoderma Gangrenosum

Ulcer

Violaceous Border

Pathergy

Neutrophilic Dermatosis