SHM Converge Scientific Abstract ePoster Gallery-Atrial Fibrillation Predicts Mace in Transcatheter Tricuspid Valve Procedures

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This retrospective cross-sectional study examined whether atrial fibrillation (AF) predicts adverse outcomes in patients undergoing transcatheter tricuspid valve procedures (TTVP) for tricuspid regurgitation. Using the National Inpatient Sample from January 2017 to December 2019, the authors compared hospitalized TTVP patients with and without AF. They used chi-square testing for baseline differences and multivariable logistic regression adjusted for age, sex, and race.<br /><br />The main outcome was major adverse cardiovascular events (MACE). The study found that AF was associated with significantly worse cardiovascular outcomes after TTVP. Specifically, AF increased the odds of MACE by 3.29 times and increased the odds of heart failure by 3.05 times compared with patients without AF. However, mortality was not statistically different between groups: 3.51% in non-AF patients versus 2.74% in AF patients.<br /><br />The authors conclude that AF is an independent predictor of adverse cardiovascular events, particularly heart failure, in patients undergoing TTVP. Because TTVP is a newer and less common procedure, data on long-term and in-hospital outcomes remain limited. The study suggests that future research should identify predictors of outcomes among TTVP patients with AF and potentially develop a risk score similar to those used in transcatheter aortic valve replacement populations.<br /><br />The authors also note important limitations, including the retrospective design and potential confounding factors.

Asset Subtitle

Christopher N. Matthews

Meta Tag

Author List Abel Casso Dominguez, Christopher N. Matthews, James Choi, Sara Diaz Saravia

Category Research

Concept Transcatheter Tricuspid Valve Procedure

Concept Atrial Fibrillation

Concept Tricuspid Regurgitation

Concept Major Adverse Cardiovascular Events

Concept Heart Failure

Distinguished Non-Finalist

Presenter Organization Icahn School of Medicine at Mount Sinai

Presenting Author Christopher N. Matthews

Track Outcomes Research

Keywords

atrial fibrillation

transcatheter tricuspid valve procedures

tricuspid regurgitation

major adverse cardiovascular events

heart failure

National Inpatient Sample

retrospective study

multivariable logistic regression

in-hospital outcomes

risk prediction

Transcatheter Tricuspid Valve Procedure

Atrial Fibrillation

Tricuspid Regurgitation

Major Adverse Cardiovascular Events

Heart Failure