SHM Converge Scientific Abstract ePoster Gallery-Association of Ventricular Tachycardia Burden With in-Hospital Mortality

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This retrospective cohort study examined whether ventricular tachycardia (VT) burden predicts 30-day in-hospital mortality among 5,679 adult ICU patients at a single center (2013–2015). Unlike earlier studies, the authors used a validated UCSF algorithm with manual annotation to identify true VT events, reducing false positives common in ECG monitoring data.<br /><br />Patients were grouped by VT burden: 0, 1–2, or 3 total true VT events. The study used Kaplan-Meier survival analysis and multivariable logistic regression, adjusting for demographics, cardiac comorbidities, and ICU type. Survival differed significantly across VT categories (log-rank P < 0.0001). Compared with patients without VT, those with 1–2 VT events had higher odds of 30-day in-hospital mortality (adjusted OR 2.50, 95% CI 1.89–3.31), and those with 3 VT events had even higher odds (adjusted OR 3.52, 95% CI 2.29–5.40).<br /><br />The findings suggest a dose-response relationship: as VT burden increases, so does the risk of in-hospital death. The authors conclude that VT burden is a significant predictor of mortality even after adjustment for clinical factors. They also suggest that patients with 3 VT events may benefit from earlier intervention.<br /><br />The study highlights the need for a standard definition of VT burden and notes that current ECG monitoring systems generally do not calculate or display VT burden, despite its potential clinical value for identifying high-risk ICU patients.

Asset Subtitle

Jackeline P. Vajta Gomez

Meta Tag

Author List David Mortara, Fabio Badilini, Geoff Tison, Jackeline P. Vajta Gomez, Michele M. Pelter PhD, Priya A. Prasad

Category Research

Concept Ventricular Tachycardia

Concept Ventricular Tachycardia Burden

Concept 30-Day In-Hospital Mortality

Concept True VT Events

Concept Dose-Response Relationship

Distinguished Non-Finalist

Presenter Organization Ucsf

Presenting Author Jackeline P. Vajta Gomez

Track Outcomes Research

Keywords

ventricular tachycardia

VT burden

ICU mortality

30-day in-hospital mortality

retrospective cohort study

ECG monitoring

logistic regression

Kaplan-Meier analysis

dose-response relationship

high-risk ICU patients

Ventricular Tachycardia

Ventricular Tachycardia Burden

30-Day In-Hospital Mortality

True VT Events

Dose-Response Relationship