SHM Converge Scientific Abstract ePoster Gallery-Association Between Lumens and Picc Complications in Cancer Patients

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This retrospective cohort study examined whether the number of lumens in peripherally inserted central catheters (PICCs) affects complication risk in hospitalized adults with active malignancy. Data came from 5,609 PICC placements across 65 Michigan hospitals between 2014 and 2023. Outcomes included symptomatic upper-extremity venous thromboembolism (UE-VTE), laboratory-confirmed central line-associated bloodstream infection (CLABSI), catheter occlusion, and a composite of all three, assessed through chart review and 30-day follow-up.<br /><br />Most PICCs were double lumen (63.3%), followed by single lumen (28.7%) and triple lumen (8.0%). Complication rates increased with more lumens. Compared with single-lumen PICCs, double-lumen PICCs had significantly higher odds of UE-VTE, CLABSI, catheter occlusion, and the composite outcome. Compared with double-lumen PICCs, triple-lumen PICCs had significantly higher odds of CLABSI, catheter occlusion, and the composite outcome, but not UE-VTE.<br /><br />Key adjusted odds ratios showed:<br />- Double vs. single: UE-VTE 2.13, CLABSI 1.75, occlusion 4.00, composite 2.86<br />- Triple vs. double: UE-VTE 1.31, CLABSI 1.93, occlusion 1.55, composite 1.77<br /><br />Overall, the study found that more PICC lumens were associated with greater complication risk in patients with active cancer. The authors conclude that, when possible, single-lumen PICCs should be preferred over multi-lumen catheters in this high-risk population.

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David Paje

Meta Tag

Author List Alice Cusick, Caitlin Tatarcuk, David Paje, Elizabeth McLaughlin, Jennifer K. Horowitz, Lakshmi Swaminathan, Megan Heath, Scott A. Flanders, Scott Kaatz, Steven J. Bernstein, Vineet Chopra

Category Research

Concept PICC Line

Concept PICC Lumen Number

Concept Catheter Lumen

Concept Complication

Concept Active Cancer

Distinguished Non-Finalist

Presenter Organization University of Michigan

Presenting Author David Paje

Track Patient Safety

Keywords

peripherally inserted central catheters

PICC lumens

active malignancy

hospitalized adults

upper-extremity venous thromboembolism

central line-associated bloodstream infection

catheter occlusion

retrospective cohort study

catheter complications

single-lumen PICC

PICC Line

PICC Lumen Number

Catheter Lumen

Complication

Active Cancer