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Aorto-Right Ventricular Fistula After Transcathete ...
Aorto-Right Ventricular Fistula After Transcatheter Aortic Valve Replacement Presenting as Cardiac Arrest: A Case for Hospitalists
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This case describes what appears to be the first reported aorto-right ventricular fistula (ARVF) after transcatheter aortic valve replacement (TAVR) presenting as cardiac arrest. TAVR is a major treatment for severe aortic stenosis, but rare complications like ARVF may be missed because early symptoms can be subtle.<br /><br />The patient was a 69-year-old man with severe aortic stenosis, heart failure with reduced ejection fraction, and end-stage renal disease who had undergone an uncomplicated TAVR four weeks earlier. During routine hemodialysis, he became dizzy and developed monomorphic ventricular tachycardia, progressing to cardiac arrest requiring defibrillation and intubation.<br /><br />On arrival to the ICU, he had a wide pulse pressure and a continuous murmur throughout systole and diastole, raising concern for paravalvular leak or aortic regurgitation. Transthoracic echocardiography showed continuous flow from the aortic root to the right ventricle, suggesting an aorto-RV fistula. Transesophageal echocardiography confirmed a 6 mm fistula near the prosthetic valve. He was transferred to a tertiary center for planned percutaneous closure with an Amplatzer vascular plug, but his condition rapidly deteriorated and he died before the procedure could be performed.<br /><br />The proposed mechanism was a left-to-right shunt causing reduced systemic vascular resistance and diastolic blood pressure, impaired coronary perfusion, and increased risk of ventricular arrhythmias. Hemodialysis-related hypovolemia likely worsened myocardial ischemia and contributed to arrest.<br /><br />The key message is that ARVF after TAVR, though extremely rare, can cause fatal hemodynamic compromise. Early recognition, prompt echocardiographic assessment, and rapid referral for intervention are critical. Hospitalists caring for post-TAVR patients play an important role in identifying this complication early.
Asset Subtitle
FNU Pratishruti
Meta Tag
Author List
Darpan Bansal, FNU Pratishruti, Pushan Aggarwal, Ram Bhutani
Category
Clinical Vignettes
Concept
Aorto-Right Ventricular Fistula
Concept
Transcatheter Aortic Valve Replacement
Concept
Echocardiography
Concept
Cardiac Arrest
Concept
Hemodynamic Instability
Distinguished
Non-Finalist
Presenter Organization
Johns Hopkins University School of Medicine
Presenting Author
FNU Pratishruti
Track
Adult
Keywords
transcatheter aortic valve replacement
aorto-right ventricular fistula
cardiac arrest
ventricular tachycardia
aortic stenosis
echocardiography
paravalvular leak
hemodialysis
left-to-right shunt
Amplatzer vascular plug
Aorto-Right Ventricular Fistula
Transcatheter Aortic Valve Replacement
Echocardiography
Cardiac Arrest
Hemodynamic Instability
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