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Alcohol Use Disorder and the Inpatient Treatment L ...
Alcohol Use Disorder and the Inpatient Treatment Landscape
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This Mayo Clinic report examines inpatient opportunities to improve treatment for alcohol use disorder (AUD) by increasing prescribing of medications for AUD (MAUD). AUD affects millions of Americans, yet only about 5% receive treatment, despite evidence that the three FDA-approved medications—naltrexone, acamprosate, and disulfiram—are effective.<br /><br />The study reviewed adult AUD encounters across three major Mayo Clinic centers from April 2018 to October 2023. After exclusions, 14,382 inpatient encounters were analyzed. Researchers assessed prescribing patterns for newly initiated MAUD and compared rates across patient and hospitalization subgroups using chi-square analysis.<br /><br />Overall, 92% of encounters resulted in no MAUD prescription, 5% in a new prescription, and 3% involved patients already on MAUD before admission. The findings showed significant differences in prescribing rates by demographic and clinical factors. MAUD initiation was more common among White patients than non-White patients, and among men than women. Older patients also received MAUD more often than younger adults.<br /><br />Hospital-related factors strongly influenced prescribing. Patients on teaching, medicine, psychiatry, or family medicine services, as well as those receiving care management or psychiatry consults, were more likely to be started on MAUD. Prescribing was also higher when AUD was the primary diagnosis and when length of stay exceeded five days. Emergency encounters had especially low initiation rates compared with inpatient admissions.<br /><br />The authors conclude that inpatient hospitalization is a critical but underused opportunity to start evidence-based AUD treatment. They identify notable disparities in prescribing and emphasize the need for targeted quality improvement efforts to increase MAUD use, especially in groups and settings with lower prescribing rates.
Asset Subtitle
Neela Nataraj
Meta Tag
Author List
John Ratelle, Neela Nataraj
Category
Research
Concept
Alcohol Use Disorder
Concept
Medication for Alcohol Use Disorder
Concept
Hospitalized Patient
Concept
Naltrexone
Concept
Acamprosate
Distinguished
Non-Finalist
Presenter Organization
Mayo Clinic
Presenting Author
Neela Nataraj
Track
Quality Improvement
Keywords
alcohol use disorder
MAUD
naltrexone
acamprosate
disulfiram
inpatient treatment
prescribing disparities
Mayo Clinic
hospitalization
quality improvement
Alcohol Use Disorder
Medication for Alcohol Use Disorder
Hospitalized Patient
Naltrexone
Acamprosate
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