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A Splinter's Spiral: an Unlikely Case of Metastat ...
A Splinter's Spiral: an Unlikely Case of Metastatic Methicillin Sensitive Staph Aureus Bacteremia in a Young Immunocompetent Male
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This case report describes a previously healthy 34-year-old man who developed severe methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia originating from left index finger cellulitis. He presented with progressive shortness of breath, chest pain, and worsening finger pain, erythema, and drainage. After admission for sepsis, he underwent incision and drainage with partial finger amputation; blood and wound cultures grew MSSA.<br /><br />Despite treatment, his illness rapidly complicated. By hospital day 2, he developed chest pain concerning for pericarditis, though transthoracic echocardiography showed no endocarditis. On day 3, he acutely worsened with fever, dyspnea, and chest pain. CT imaging revealed bilateral loculated pleural effusions and enlarging cavitary lung lesions, consistent with septic pulmonary emboli, even though repeat blood cultures were negative and transesophageal echocardiography still showed no endocarditis. Chest tubes were placed on day 4, draining exudative fluid; pleural fluid cultures and cytology were negative. He required ongoing drainage and received antibiotic therapy adjustments including cefepime, cefazolin, vancomycin, and linezolid. A MIST2 protocol was used to improve pleural drainage.<br /><br />Workup for immunocompromising conditions was unrevealing, and the surgical site remained controlled. Chest tube removal was complicated by pneumothorax on day 12, but he recovered and was discharged on day 15. Follow-up CT one week later showed improvement in cavitary lesions and pleural effusions, and he completed a one-month antibiotic course with cephalexin.<br /><br />The report highlights that MSSA bacteremia can cause serious metastatic complications even in immunocompetent patients without typical risk factors such as diabetes, dialysis, IV drug use, or autoimmune disease. Persistent fever beyond 72 hours and community-acquired infection are emphasized as warning signs for complicated bacteremia.
Asset Subtitle
Yasmeen A. Abdo
Meta Tag
Author List
Ana Natale-Pereira, Brian Kim, Yasmeen A. Abdo
Category
Clinical Vignettes
Concept
MSSA Bacteremia
Concept
Staphylococcus aureus Bacteremia
Concept
Complicated Bacteremia
Concept
Septic Pulmonary Emboli
Concept
Blood Culture
Distinguished
Non-Finalist
Presenter Organization
Rutgers/NJMS
Presenting Author
Yasmeen A. Abdo
Track
Adult
Keywords
MSSA bacteremia
Staphylococcus aureus
cellulitis
sepsis
septic pulmonary emboli
cavitary lung lesions
pleural effusion
pericarditis
chest tube drainage
immunocompetent patient
MSSA Bacteremia
Staphylococcus aureus Bacteremia
Complicated Bacteremia
Septic Pulmonary Emboli
Blood Culture
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