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A Not-So Fortuitous Case of Mycobacterium
A Not-So Fortuitous Case of Mycobacterium
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Pdf Summary
This case describes a 66-year-old man with ESRD on home peritoneal dialysis who developed abdominal pain, distension, fever, and altered mental status after accidentally removing his PD catheter. Initial evaluation suggested peritonitis, and he was started on empiric cefepime and vancomycin. Although blood cultures were negative, repeat peritoneal fluid culture grew acid-fast bacilli, later identified as <strong>Mycobacterium fortuitum</strong>, a rare nontuberculous mycobacterium found in soil and water. The diagnosis was challenging because M. fortuitum can be slow to grow and may appear culture-negative early in the course. The report emphasizes the importance of <strong>acid-fast staining</strong> and <strong>prolonged culture observation</strong> to avoid delayed recognition. Once identified, the patient improved after treatment was changed to imipenem, levofloxacin, and TMP-SMX. Because M. fortuitum can infect tunneled lines and cause persistent infection, his PD catheter was removed and he was transitioned to hemodialysis. He received 8 weeks of inpatient antibiotics and was discharged on 6 additional months of oral linezolid, levofloxacin, and azithromycin. The case highlights that ESRD patients are at increased risk for mycobacterial infection and that M. fortuitum should be considered in <strong>refractory or culture-negative peritonitis</strong>. Early diagnosis, catheter removal, and prolonged multidrug therapy are key to successful treatment and preventing complications.
Asset Subtitle
Evan Raff
Meta Tag
Author List
Christopher A. Caulfield, Evan Raff, Hannah Pollock, Lara Phipps, Meg Johnson, Rachel Lile-King
Category
Clinical Vignettes
Concept
Mycobacterium fortuitum
Concept
Peritonitis
Concept
Peritoneal Fluid Culture
Concept
Catheter Removal
Concept
End-stage Kidney Disease
Distinguished
Non-Finalist
Presenter Organization
University of North Carolina School of Medicine
Presenting Author
Evan Raff
Track
Adult
Keywords
Mycobacterium fortuitum
peritonitis
peritoneal dialysis
ESRD
acid-fast bacilli
nontuberculous mycobacteria
catheter removal
culture-negative infection
multidrug therapy
hemodialysis
Mycobacterium fortuitum
Peritonitis
Peritoneal Fluid Culture
Catheter Removal
End-stage Kidney Disease
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