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A Case of Presumed Strep Pneumoniae Aortitis
A Case of Presumed Strep Pneumoniae Aortitis
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A 70-year-old man with CAD, hypertension, and hyperlipidemia presented with two months of weight loss, nausea, and worsening lower abdominal pain radiating to the back. CT angiogram showed abnormal soft tissue enhancement around the infrarenal abdominal aorta, raising concern for aortitis. He did not meet SIRS criteria, but inflammatory markers were elevated, so blood cultures were obtained and empiric antibiotics started.<br /><br />The differential included infectious, rheumatologic, and malignant causes. Rheumatologic testing was negative, and biopsy was not feasible. Rapid blood culture PCR was positive for Streptococcus pneumoniae, and later cultures confirmed pneumococcal bacteremia. Despite an extensive search, no infection source was identified.<br /><br />On hospital day 10, worsening abdominal pain and rising inflammatory markers prompted repeat imaging, which revealed a penetrating atherosclerotic ulcer of the infrarenal aorta, a form of acute aortic syndrome. Vascular surgery was consulted, and the patient underwent endovascular aortic repair (EVAR) on hospital day 11. He was discharged in stable condition on hospital day 22 with plans for six weeks of IV ceftriaxone.<br /><br />The case emphasizes that infectious aortitis is an uncommon but serious cause of abdominal pain and may present without classic sepsis features. Blood cultures can be critical when tissue diagnosis is unavailable. Infectious aortitis can progress rapidly to aneurysm or ulceration, so early vascular surgery involvement, serial abdominal exams, and repeat imaging are important.
Asset Subtitle
Evan L. Bale
Meta Tag
Author List
Evan L. Bale, Matthew Wofford
Category
Clinical Vignettes
Concept
Infectious Aortitis
Concept
Blood Culture
Concept
Polymerase Chain Reaction
Concept
Abdominal Pain
Concept
Systemic Symptoms
Distinguished
Non-Finalist
Presenter Organization
University of Colorado Department of Hospital Medicine
Presenting Author
Evan L. Bale
Track
Adult
Keywords
infectious aortitis
Streptococcus pneumoniae
pneumococcal bacteremia
abdominal pain
infrarenal aorta
penetrating atherosclerotic ulcer
endovascular aortic repair
CT angiogram
blood cultures
IV ceftriaxone
Infectious Aortitis
Blood Culture
Polymerase Chain Reaction
Abdominal Pain
Systemic Symptoms
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