Prevention of Surgical Site Infections-References

References

Pdf Summary

The document "Prevention of Surgical Site Infections (2024-2027)" provides an extensive reference list supporting evidence-based practices for reducing surgical site infections (SSIs). It emphasizes guidelines and research related to antimicrobial prophylaxis, wound care, and infection control measures in surgery.<br /><br />Key themes include the importance of proper surgical wound classification, updated antimicrobial prophylaxis guidelines by major health societies, and addressing antimicrobial resistance challenges. The references highlight the role of allergy evaluation, particularly regarding penicillin allergies, in optimizing antibiotic use and reducing SSI risks. Practice-oriented studies on antimicrobial dosing, timing, and duration underline the need for stewardship to balance infection prevention and resistance.<br /><br />Non-pharmacologic measures are addressed, including skin antisepsis comparing chlorhexidine-alcohol versus povidone-iodine, impacts of glove perforation, hair removal methods, glycemic control during and after surgery, and maintaining perioperative normothermia and oxygenation to reduce infection risk. The role of smoking cessation and diabetes management is considered critical in wound healing and SSI reduction.<br /><br />Several references focus on nasal carriage of Staphylococcus aureus as a significant source of SSIs, particularly methicillin-resistant Staphylococcus aureus (MRSA). Prophylactic interventions like intranasal mupirocin application and universal MRSA screening are supported by randomized controlled trials and systematic reviews, demonstrating efficacy in reducing postoperative infections.<br /><br />The document also references national and international guidelines such as those from CDC, ACOG, and the American College of Surgeons that consolidate best practices in SSI prevention. It underscores the importance of bundled interventions combining antimicrobial stewardship, screening, antisepsis, and patient risk factor management.<br /><br />Overall, the references collectively provide a comprehensive foundation for current and future surgical infection prevention strategies, promoting multidisciplinary approaches to improve surgical outcomes and patient safety.

Keywords

Surgical Site Infections

Antimicrobial Prophylaxis

Wound Care

Infection Control

Antimicrobial Resistance

Penicillin Allergy Evaluation

Skin Antisepsis

MRSA Screening

Perioperative Normothermia

Bundled Interventions